Oct 30 2007

Detecting aortic aneurysm through Blood test

Published by abi at 12:03 am under cardiac

 A simple blood test may accurately detect thoracic aortic aneurysm, which gives little warning and is almost always fatal if untreated, U.S. researchers say.

Dr. John Elefteriades, of Yale University School of Medicine in New Haven, Conn., says thoracic aortic aneurysm disease occurs  in the part of the aorta that passes through the chest and only one in 20 patients has symptoms before internal rupture occurs — once the aneurysm ruptures, a person can go into shock and die from internal bleeding.

Elefteriades and his colleagues at Yale School of Medicine, Applied Biosystems and Celera Diagnostics took blood samples from 58 persons diagnosed with thoracic aortic aneurysm disease and 36 spouses who did not have the disease.

The study, published in Public Library of Science, found that by using a gene expression profiling technology, the researchers identified a 41-gene signature in blood cells that distinguishes thoracic aortic aneurysm patients from those without the disease.

“It has become increasingly evident that the immune system plays a pivotal role in the development of aortic aneurysms,” Elefteriades said in a statement. “We thus hypothesized that gene expression patterns in peripheral blood cells may reflect thoracic aortic aneurysm disease status.”

Surgical correction of vascular defects is safe and effective for many patients in whom less invasive procedures are not adequate. The common conditions that need surgical interventions are Aneurysms & Varicose Veins.

The other less common vascular diseases which need surgical intervention are:
 Arteriosclerosis obliterans
 Aortoiliac occlusive disease
 Superficial femoral occlusive disease
 Tibial artery disease
 Deep venous thrombosis

We at Globe Health Tours, are associated with the best cardiologists in the world, well experienced and well specialised in complete cardiac care. 

News Daily, Globe Health Tours

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