May 08 2008
Stem cell researches to generate liver and bone cells
May 8: Researchers are trying to find a useful way to cure liver disease by effectively using embryonic stem cells. This will help to minimise the need for transplantation. This innovative research is one of two projects at Edinburgh University and it is funded with £3.6m from the Medical Research Council (MRC) and Scottish Enterprise. The second project also makes use of the embryonic stem cells to repair damaged bone. Diseases related to liver are the fifth most common cause of death in the UK.
“Once the liver cells from embryonic cells are successfully developed it will revolutionise the scope of treatment and pave the way for several new therapies and drugs for both liver and other organs. Eventually it will lead to a stem cell based regeneration of liver cells,” said Professor John Iredale of the MRC Centre for Regenerative Medicine at the University of Edinburgh.
He further added that the research is capable of playing a crucial role in reducing the number of organ transplant and will minimise the level of traumatic treatment of the patients for whom transplantation is the only option. Now the researchers are trying to find how liver cells could be developed from embryonic stem cells and the ways in which it can be used effectively for the treatment of acute and chronic liver disease.
The second research that receives £1.7m funding will help in isolation of embryonic stem into cells that are capable of developing into bone and cartilage.
While commenting on this Dr Brendon Noble of the Medical Research Council Centre for Regenerative Medicine said: “Cartilage damage due to injuries or diseases like osteoarthritis is a major health problem in the UK. Prevention of cartilage from breaking down or by repairing it will potentially reduce hip replacement surgeries. We are trying to find a fruitful way to heal the bones using stem cells that could enhance the quality of life of the patients.”
We could expect the findings of these researches will bring great relief for the patients who are suffering from bone related diseases.